Home EMIJ The role of iodine vs selenium on the rising trend of autoimmune thyroiditis in iodine sufficient countries. Opinion Special Issue Thyroid Research. Keywords: iodine, selenium, autoimmune thyroiditis, thyroid autoimmunity. The role of iodine and the balancing effect of selenium on thyroid physiology Iodine, a trace element found mostly in the soil of coastal areas in the form of water soluble iodide ion I- , is essential for the production of thyroid hormones.
The author has nothing to declare regarding this opinion article. Fountoulakis S, Tsatsoulis A. On the pathogenesis of autoimmune thyroid disease: a unifying hypothesis. Clin Encdocrinol. Tomer Y, Huber A. The etiology of autoimmune thyroid disease: a story of genes and environment.
J Autoimmun. Luo Y, kawashima, A, Ishido Y, et al. Iodine excess as an environmental risk factor for autoimmune thyroid disease. Int J Mol Sci. High prevalence of autoimmune thyroiditis in school children after elimination of iodine deficiency in North Western Greece.
Iodine intake as a determinant of thyroid disorders in populations. NIlsson M. Iodine handling by the thyroid epithelial cell. Exp Clin Endocrinol diabetes. Role of iodine in thyroid physiology.
Carrasco MN. Thyroid hormone synthesis. In: The Thyroid. PA: Lippincott Wilkins; Selenium, the thyroid, and the endocrine system. Endocr Rev. Rayman M. The importance of selenium to human health. Role of iodine, selenium and other micronutrrients in thyroid function and disorders. The effect of iodine restriction on thyroid function in patients with hypothyroidism due to Hashimoto's thyroiditis.
Yonsei Med J. Experimental study on the effects of chronic iodine excess on thyroid function, structure and autoimmunity in autoimmune -prone NOD. H-2 h4 mice. Clin Exp Med. The role of iodine in thyroid autoimmunity: from chickens to animals: a review. Carayanniotis G. Molecular parameters linking thymoglobulin iodination with autoimmune thyroiditis.
Negro R. Selenium and thyroid autoimmunity. An epidemiological study on the relationship between selenium and thyroid function in areas with different iodine intake.
Zhonghua Yi Xue Za Zhi. Low population selenium status is associated with increased prevalence of thyroid disease. Seaweed is a particularly good source of iodine. We humans can tolerate rather large amounts of iodine. Radioactive iodine may accumulate in the thyroid gland and cause hypothyroidism plus other types of damage and cancer.
It is controversial to give iodine supplements to people with thyroid disorders like Hashimoto's disease that causes low metabolism. Some get worse and show sudden signs of elevated antibody production that can attack the thyroid gland. Others who take iodine supplements show clear signs of improvement with lower antibody levels. There is increasing evidence that simultaneous intake of selenium supplements contributes to an improved balance between the two trace elements, both of which are important for regulating thyroid hormones but also help detoxify the body when it gets exposed to mercury, fluoride, chlorine, and bromium.
In addition, selenium is a powerful antioxidant that protects the thyroid gland against free radicals and the type of inflammation that is usually seen with autoimmune thyroid diseases like Hashimoto's and Graves'. People who suffer from these two conditions may benefit from reading about the importance of iodine and selenium supplementation and discussing this with a knowledgeable physician. Anne Krejbjerg. Thyreoidea Landsforeningen Pernille Lund: Har du problemer med stofskiftet?
Stop stofskiftevanviddet. Selenanvendelse i dansk landbrug. Search for more information Click here if you want to search for more information about selenium. International Coenzyme Q10 Association q10facts. How iodine and selenium regulate thyroid hormones The thyroid gland that is located on the front side of the throat produces two different thyroid hormones.
Mercury and other heavy metals increase the need for selenium Selenium atoms bind to mercury atoms and form mercury selenide, a non-toxic compound which the body can excrete. Iodine enrichment of salt - but still signs of iodine deficiency In year , mandatory iodine enrichment of salt was introduced in Denmark because the iodine intake among Danes was lower than international recommendations.
Selenium deficiency and poor utilization may be a result of various factors such as: Poor diets without fish and shellfish Lack of selenium and an imbalance between iodine and selenium High consumption of goitrogens like soy beans edamame beans, tofu, soy milk etc. Also dirt- and water-repellent PFCs that are found in Teflon, parchment paper, pizza trays, impregnation etc.
Background: The New Zealand population has both marginal selenium status and mild iodine deficiency. Adequate intakes of iodine and selenium are required for optimal thyroid function. Objective: The aim of the study was to determine whether low selenium and iodine status compromises thyroid function in an older New Zealand population.
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